PEREGRINE I offers dramatically improved discovery power in comparison to other
conventional CE systems without the use of molecular labels. This is achieved by the
ombination of substantially enhanced resolution, sensitivity and quantification power of the
instrument, along with the digital output of data delivered as clearly resolved separations. The
system has proven capability in almost all modes of CE. It allows analyte molecular weight and
concentration to be assigned and absolute measurements can be performed using calibrating
markers. Supplied with the instrument is a powerful customized suite of data handling and
analysis tools.
conventional CE systems without the use of molecular labels. This is achieved by the
ombination of substantially enhanced resolution, sensitivity and quantification power of the
instrument, along with the digital output of data delivered as clearly resolved separations. The
system has proven capability in almost all modes of CE. It allows analyte molecular weight and
concentration to be assigned and absolute measurements can be performed using calibrating
markers. Supplied with the instrument is a powerful customized suite of data handling and
analysis tools.
PEREGRINE I
HPCE instrument
UV light is directed from the source via filters and optical components at the capillary window.
The detector assembly contains a photodiode array of 512 detection points.
Optical Rail
Capillary block
For most electrophoretic separations a fused silica capillary coated with polyimide on the
outside is used. The separation lengths can be set from 20 cm to 70 cm by selecting the
appropriate route in the capillary block.
Data Analysis
LABEL FREE
INTRINSIC
IMAGING
LFII®
The data analysis of biomolecules performed using the deltaDOT PEREGRINE I system is
enabled by proprietary Equiphase Vertexing Algorithm (EVA) and Generalised Separation
Transform (GST) algorithms. GST is a method of combining the data from the multiple
pixels in a natural way which preserves the peak shape information of the
electropherograms while at the same time maximising the signal-to-noise ratio. A factor of
10 increase in signal-to-noise using GST as compared to using single point detection, is
typically observed
enabled by proprietary Equiphase Vertexing Algorithm (EVA) and Generalised Separation
Transform (GST) algorithms. GST is a method of combining the data from the multiple
pixels in a natural way which preserves the peak shape information of the
electropherograms while at the same time maximising the signal-to-noise ratio. A factor of
10 increase in signal-to-noise using GST as compared to using single point detection, is
typically observed
13 August 2012 Texas A&M System Awarded National Center for
Innovation
deltaDOT Ltd. is a partner in BARDA funded international
consortium
$285.6 million public-private partnership to enhance the nation’s
biosecurity preparedness and create jobs in Texas
COLLEGE STATION, Texas – John Sharp, chancellor of The Texas
A&M University System, today announced that the A&M System
has been awarded a contract to develop one of three U.S.
Department of Health and Human Services Centers for Innovation
in Advanced Development and Manufacturing. The $285.6 million
contract includes an initial investment of $176.6 million from the
U.S. government, with the remainder cost-shared by commercial
and academic proposal partners.
2nd August 2012 deltaDOT Ltd. awarded Technology Strategy
Board grant
deltaDOT Ltd, announced today that the government-backed
Technology Strategy Board has awarded the company a feasibility
study award for the applicationof its Label Free Intrinsic Imaging
technology to bioprocess analytics. The project “Rapid low cost
formulation screening for protein self-interaction based on High
Performance Capillary Electrophoresis” is a feasibility study that
addresses the need for a costeffective,
user-friendly, automated platform technology allowing rapid
screening for protein selfinteractions.
A&M University System, today announced that the A&M System
has been awarded a contract to develop one of three U.S.
Department of Health and Human Services Centers for Innovation
in Advanced Development and Manufacturing. The $285.6 million
contract includes an initial investment of $176.6 million from the
U.S. government, with the remainder cost-shared by commercial
and academic proposal partners.
2nd August 2012 deltaDOT Ltd. awarded Technology Strategy
Board grant
deltaDOT Ltd, announced today that the government-backed
Technology Strategy Board has awarded the company a feasibility
study award for the applicationof its Label Free Intrinsic Imaging
technology to bioprocess analytics. The project “Rapid low cost
formulation screening for protein self-interaction based on High
Performance Capillary Electrophoresis” is a feasibility study that
addresses the need for a costeffective,
user-friendly, automated platform technology allowing rapid
screening for protein selfinteractions.