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deltaDOT is a spin out company from Imperial College London UK - a team of scientists and  engineers dedicated to the advancement of analytical techniques using patented methods and  instrumentation in High Performance Capillary Electrophoresis (HPCE). We design and  produce HPCE instruments which we are marketing worldwide. We also use the same  instruments to offer Analytical Services and Contract Research. Our offices and laboratories  are based in the London Bioscience Innovation Centre (LBIC). 
Who we are 
HPCE instruments 
High Performance Capillary Electrophoresis (HPCE) analytical instruments are designed,  manufactured and marketed by deltaDOT. These instruments use deltaDOT’s proprietary  imaging and analysis technology called Label Free Intrinsic Imaging (LFII®). High  Performance Capillary Electrophoresis and Label Free Intrinsic Imaging applied to a CE  analytical system  offers dramatically improved discovery power in comparison to other  conventional CE systems.
deltaDOT team of scientists has developed considerable expertise in CE based analysis and in  solving clients’ analytical problems. Using our own HPCE LFII® analytical instruments we also  offer Analytical Services and Contract Research to industry and academia from our  laboratories in the London Bioscience Innovation Centre.  
Analytical Services & Contract Research 
HPCE Applications 
High Performance Capillary Electrophoresis (HPCE) is applied in Life Sciences research, drug  testing, diagnostics and bio-pharmaceutical manufacturing. This technology is used in  detection, separation and analysis of proteins, nucleic acids, carbohydrates, viruses and  bacteria, chemicals and a wide range of other analytes. More detail can be found on our  Technology pages. 
Application Notes & Downloads 
Antibody Analysis, Amino Acid Analysis, Transferrin, Small Molecules, Peptides, Complex  Protein Lysates, Recombinant Human Erythropoietin, Antibiotics in food products, Glycoforms,  DNA, RNA, Chemicals, Baculovirus Titre.  Glomerular filtration rate (GFR) determined by Iohexol clearance was developed in  collaboration with Royal Veterinary College for renal failure diagnosis in companion animals  (...more) 
13 October 2017 deltaDOT continues with Technology partnership publication (www.ttp.com)  The TTP Journal of Technology and Business Innovation provides technical insight into UK  advanced scientific businesses. New articles are now available on Water Ionic Analysis (...more)  and Nicotine Analysis (...more).  8 September 2017 deltaDOT are launching a new series of articles dD Techniques on the  capabilities of their High Performance Label Free Imaging Capillary Electrophoresis technology.  The articles offer accessible information and an insight into this unique technology which is used  worldwide to solve challenging analytical problems. A new perspective on the tools required for  the development and manufacture of monoclonal antibodies, biosimilars, stratified therapies,  viral vaccines and gene therapy vectors highlights the need for new analytical techniques.  These new perspectives are the aims which dD Techniques articles intend to deliver to a wide  range of audience (...links to article1, article2, article3)  24 August 2017 The Technology partnership publication (www.ttp.com) now includes key facts  and data on deltaDOT’s High Precision Capillary Electrophoresis advanced technology. The TTP  Journal of Technology and Business Innovation provides technical insight into UK advanced  scientific businesses (...more) 3rd July 2017 Future Targeted Healthcare Manufacturing. deltaDOT announce their  participation in the new EPSRC funded Future Targeted Healthcare Manufacturing Hub, led by  UCL (...more). The Hub will address the manufacturing, business and regulatory challenges to  ensure that new targeted biological medicines can be developed quickly and manufactured at  affordable costs (...more).   24th January 2017 – deltaDOT Ltd. announces compliance with CFR 21 part 11 of USA’s Food  and Drug Administration. deltaDOT now offers an upgraded version of its control and analysis  software which has been designed to aid users of deltaDOT’s HPCE-512 Hig Performance  Capillary Electrophoresis instrument in achieving compliance with CFR 21 part 11.The upgrade  package contains controls to help meet the stringent requirements of CFR 21 part 11 including  the system access by authorised personel only, maintaining audit trails of user actions,  generating complete and protected data files and the application of electronic signatures to data  (...more)  20 Sep 2016 National Health Service Quality Control North West (QCNW) Liverpool  labs  presented the data on monoclonal antibody stability trials based on deltaDOT’s Capillary  Electrophoresis (CE) technology  and expertise. They state that CE technology is suitable for  monitoring the stability of monoclonal antibodies and can perform purity and charge analysis with  high resolution and repeatability. They conclude that CE can replace other techniques commonly  used for this analysis IEC and SDS PAGE (link to the poster).  3rd July 2016 Monoclonal Antibody Stability Trials using deltaDOT HPCE-512 technology  reported by Dr. Deepika Devanur. Now available in pdf slide format on our website (...more)  4th March 2016, FDA CFR21/11 Compliance - deltaDOT’s progress continues with the  implementation of the software quality system while the P3 controller system management  software and the P3EVA analysis package had their compliance completed previously deltaDOT  engineers are working with Optra systems of California (...more)  26th January 2016, National Health Service Quality Control North West (QCNW) Liverpool  Labs are to perform monoclonal antibody stability trials, utilising deltaDOT Ltd. technology and  expertise to aid the study.     4th February 2016 Webinar: Improve your Monoclonal Antibodies Analysis. Live webinar on  analysing mAbs from production to patient. Given jointly by Horiba Scientific and deltaDOT Ltd.  Presented by Dr. Deepika Devanur (...registration site) 
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